In Rome, relive epic gladiator battles in the iconic Colosseum, and in Bilbao, behold the undulating, titanium-clad edifice by Frank Gehry that houses the Guggenheim Museum. Stand at the crossroads of the world's three great religions in Jerusalem's Old Town, and gaze across Athens from the magnificent Acropolis, where the seeds of democracy were planted over two centuries ago.

Even hyperbole takes a holiday in the Mediterranean. Gorge on over 2,500 years of history in Cartegena, bask in all-things-Gaudi in Barcelona, overdo it on Italian culture and food, get your Greek Isles on, but mostly, prepare to be changed.